Analysis of DNA adducts by capillary methods coupled to mass spectrometry: a perspective

被引：51

作者：

Apruzzese, WA

Vouros, P ^{[1
]}

机构：

[1] Northeastern Univ, Dept Chem, Boston, MA 02115 USA

[2] Northeastern Univ, Barnett Inst, Boston, MA 02115 USA

来源：

JOURNAL OF CHROMATOGRAPHY A | 1998年 / 794卷 / 1-2期

关键词：

reviews; mass spectrometry; DNA adducts;

D O I：

10.1016/S0021-9673(97)00820-0

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

The analysis of DNA adducts, important molecular biomarkers indicative of potential cellular damage by covalent attachment to DNA, is discussed. The paper focusses on a discussion of the current status in the analysis of DNA adducts via the use of capillary high-performance liquid chromatographic and capillary electrophoretic methods coupled to tandem mass spectrometry. (C) 1998 Elsevier Science B.V.

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收藏

页码：97 / 108

页数：12

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