A stereoselective three-component reaction:: KAl(SO4)2•12H2O, an efficient and reusable catalyst for the one-pot synthesis of cis-isoquinolonic acids

被引:117
作者
Azizian, J [1 ]
Mohammadi, AA [1 ]
Karimi, AR [1 ]
Mohammadizadeh, MR [1 ]
机构
[1] Shahid Beheshti Univ, Fac Sci, Dept Chem, Tehran, Iran
关键词
D O I
10.1021/jo049138g
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
KAl(SO4)(2).12H(2)O is found to catalyze efficiently the stereo-selective one-pot three-component cyclocondensation of homophthalic anhydride, aldehydes, and amines under mild conditions to afford the corresponding cis-isoquinolonic acids in good yields.
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页码:350 / 352
页数:3
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