Coscinamides A, B and C, three new bis indole alkaloids from the marine sponge Coscinoderma sp.

被引：67

作者：

Bokesch, HR

Pannell, LK

McKee, TC

Boyd, MR ^{[1
]}

机构：

[1] NCI, Lab Drug Discovery Res & Dev, Dev Therapeut Program, Div Canc Treatment & Diag,Fraderick Canc Res & De, Frederick, MD 21702 USA

[2] FCRDC, SAIC Frederick, Frederick, MD 21702 USA

[3] NIDDK, Bioorgan Chem Lab, NIH, Bethesda, MD 20892 USA

来源：

TETRAHEDRON LETTERS | 2000年 / 41卷 / 33期

基金：

美国国家卫生研究院;

关键词：

bis indole alkaloid; marine natural product; Coscinoderma;

D O I：

10.1016/S0040-4039(00)01062-5

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Three novel bis indole alkaloids, coscinamides A-C have been isolated from an extract of the marine sponge Coscinoderma sp., and their structures determined on the basis of spectral data, These compounds contain an unusual alpha-keto enamide functionality and are the first reported alkaloids from this genus, Published by Elsevier Science Ltd.

引用

页码：6305 / 6308

页数：4

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