Synthesis of multisubstituted furans, pyrroles, and thiophenes via ynolates

被引：91

作者：

Shindo, Mitsuru ^{[1
]}

Yoshimura, Yutaka

Hayashi, Maiko

Soejima, Hiroe

Yoshikawa, Takashi

Matsumoto, Kenji

Shishido, Kozo

机构：

[1] Kyushu Univ, Inst Mat Chem & Engn, Kasuga, Fukuoka 8168580, Japan

[2] Kyushu Univ, Interdisciplinary Grad Sch Engn Sci, Kasuga, Fukuoka 8168580, Japan

[3] Univ Tokushima, Grad Sch Pharmaceut Sci, Tokushima 7708505, Japan

来源：

ORGANIC LETTERS | 2007年 / 9卷 / 10期

关键词：

D O I：

10.1021/ol0705200

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An efficient synthetic method for the preparation of multisubstituted furans, thiophenes, and pyrroles using ynolates was developed. This novel formal [4 + 1] annulation by C2-C3 and C3-C4 bond formations includes cycloaddition, cyclization, decarboxylation, and dehydration as key steps.

引用

页码：1963 / 1966

页数：4

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