Synthesis of multisubstituted furans, pyrroles, and thiophenes via ynolates

被引:91
作者
Shindo, Mitsuru [1 ]
Yoshimura, Yutaka
Hayashi, Maiko
Soejima, Hiroe
Yoshikawa, Takashi
Matsumoto, Kenji
Shishido, Kozo
机构
[1] Kyushu Univ, Inst Mat Chem & Engn, Kasuga, Fukuoka 8168580, Japan
[2] Kyushu Univ, Interdisciplinary Grad Sch Engn Sci, Kasuga, Fukuoka 8168580, Japan
[3] Univ Tokushima, Grad Sch Pharmaceut Sci, Tokushima 7708505, Japan
关键词
D O I
10.1021/ol0705200
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
An efficient synthetic method for the preparation of multisubstituted furans, thiophenes, and pyrroles using ynolates was developed. This novel formal [4 + 1] annulation by C2-C3 and C3-C4 bond formations includes cycloaddition, cyclization, decarboxylation, and dehydration as key steps.
引用
收藏
页码:1963 / 1966
页数:4
相关论文
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