Structure of solid-supported lipid-DNA-metal complexes investigated by energy dispersive X-ray diffraction

被引：10

作者：

Caracciolo, G

Sadun, C

Caminiti, R

Pisani, M

Bruni, P

Francescangeli, O

机构：

[1] Univ Roma La Sapienza, Dipartimento Chim, I-00185 Rome, Italy

[2] Univ Roma La Sapienza, INFM, I-00185 Rome, Italy

[3] Univ Politecn Marche, Dipartimento Sci Mat & Terra, I-60131 Ancona, Italy

[4] Univ Politecn Marche, INFM, I-60131 Ancona, Italy

[5] Univ Politecn Marche, Dipartimento Fis & Ingn Mat & Territorio, I-60131 Ancona, Italy

来源：

CHEMICAL PHYSICS LETTERS | 2004年 / 397卷 / 1-3期

关键词：

D O I：

10.1016/j.cplett.2004.08.102

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

When mixing aqueous solutions of DNA and dioloeyl-phosphatidylcholine multilamellar liposomes in the presence of Mn2+ ions, a multilamellar liquid-crystalline phase is formed in which DNA monolayers are comprised between opposing lipid bilayers. Here, we report on a new experimental procedure resulting in the formation of solid-supported DOPC-DNA-Mn2+ complexes in the biologically relevant excess water condition. The supramolecular structure of solid-supported complexes, characterized by means of Energy Dispersive X-ray Diffraction, exhibits very similar structural properties with respect to the solution structure of the complexes as revealed by synchrotron Small Angle X-ray Scattering measurements. (C) 2004 Elsevier B.V. All rights reserved.

引用

页码：138 / 143

页数：6

共 30 条

[1] INTERACTION OF POLYNUCLEOTIDES WITH NATURAL AND MODEL MEMBRANES [J].