Epigenetic inheritance in plants

被引:602
作者
Henderson, Ian R. [1 ]
Jacobsen, Steven E. [1 ]
机构
[1] Univ Calif Los Angeles, Howard Hughes Med Inst, Dept Mol Cell & Dev Biol, Los Angeles, CA 90095 USA
基金
美国国家卫生研究院;
关键词
D O I
10.1038/nature05917
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
The function of plant genomes depends on chromatin marks such as the methylation of DNA and the posttranslational modification of histones. Techniques for studying model plants such as Arabidopsis thaliana have enabled researchers to begin to uncover the pathways that establish and maintain chromatin modifications, and genomic studies are allowing the mapping of modifications such as DNA methylation on a genome-wide scale. Small RNAs seem to be important in determining the distribution of chromatin modifications, and RNA might also underlie the complex epigenetic interactions that occur between homologous sequences. Plants use these epigenetic silencing mechanisms extensively to control development and parent-of-origin imprinted gene expression.
引用
收藏
页码:418 / 424
页数:7
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