Umbilical Cord Transplantation: Epilogue

被引：25

作者：

Broxmeyer, Hal E. ^{[1
]}

机构：

[1] Indiana Univ, Sch Med, Dept Microbiol & Immunol, Indianapolis, IN 46202 USA

来源：

SEMINARS IN HEMATOLOGY | 2010年 / 47卷 / 01期

基金：

美国国家卫生研究院;

关键词：

PLURIPOTENT STEM-CELLS; ENDOTHELIAL PROGENITOR CELLS; BLOOD CD34(+) CELLS; HEMATOPOIETIC STEM; BONE-MARROW; STEM/PROGENITOR CELLS; ENHANCES ENGRAFTMENT; REPOPULATING CELLS; PEDIATRIC-PATIENTS; PERIPHERAL-BLOOD;

D O I：

10.1053/j.seminhematol.2009.10.002

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The field of cord blood transplantation has come a long way since the first transplant more than 20 years ago. Advancements in the field will require continuing efforts to better understand hematopoietic stem and progenitor cell function and engraftment. Cautious optimism is inherent in the potential relevance and applicability of nonhematopoietic stem and progenitor cell types found in cord blood, and induced pluripotent stem cells generated from cord blood cells. Rigorous investigations and close interactions between scientific and clinical investigators are required to translate human in vitro and animal in vivo findings into clinical utility. Semin Hematol 47:97-103. (C) 2010 Published by Elsevier Inc.

引用

页码：97 / 103

页数：7

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