ClutrFree: cluster tree visualization and interpretation

被引:15
作者
Bidaut, G
Ochs, MF
机构
[1] Fox Chase Canc Ctr, Div Populat Sci, Philadelphia, PA 19111 USA
[2] CNRS, UPR 2589, Struct & Genom Informat Lab, F-13402 Marseille, France
关键词
D O I
10.1093/bioinformatics/bth307
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
ClutrFree facilitates the visualization and interpretation of clusters or patterns computed from microarray data through a graphical user interface that displays patterns, membership information of the genes and annotation statistics simultaneously. ClutrFree creates a tree linking the patterns based on similarity, permitting the navigation among patterns identified by different algorithms or by the same algorithm with different parameters, and aids the inferring of conclusions from a microarray experiment.
引用
收藏
页码:2869 / 2871
页数:3
相关论文
共 7 条
[1]   Gene Ontology: tool for the unification of biology [J].
Ashburner, M ;
Ball, CA ;
Blake, JA ;
Botstein, D ;
Butler, H ;
Cherry, JM ;
Davis, AP ;
Dolinski, K ;
Dwight, SS ;
Eppig, JT ;
Harris, MA ;
Hill, DP ;
Issel-Tarver, L ;
Kasarskis, A ;
Lewis, S ;
Matese, JC ;
Richardson, JE ;
Ringwald, M ;
Rubin, GM ;
Sherlock, G .
NATURE GENETICS, 2000, 25 (01) :25-29
[2]   Comparisons and validation of statistical clustering techniques for microarray gene expression data [J].
Datta, S ;
Datta, S .
BIOINFORMATICS, 2003, 19 (04) :459-466
[3]   ASAP: automated sequence annotation pipeline for web-based updating of sequence information with a local dynamic database [J].
Kossenkov, A ;
Manion, FJ ;
Korotkov, E ;
Moloshok, TD ;
Ochs, MF .
BIOINFORMATICS, 2003, 19 (05) :675-676
[4]   Application of Bayesian Decomposition for analysing microarray data [J].
Moloshok, TD ;
Klevecz, RR ;
Grant, JD ;
Manion, FJ ;
Speier, WF ;
Ochs, MF .
BIOINFORMATICS, 2002, 18 (04) :566-575
[5]   Bayesian decomposition - Analyzing microarray data within a biological context [J].
Ochs, MF ;
Moloshok, TD ;
Bidaut, G ;
Toby, G .
APPLICATIONS OF BIOINFORMATICS IN CANCER DETECTION, 2004, 1020 :212-226
[6]  
OCHS MF, 2003, BIOTECHNIQUES, V34, pS4
[7]   Validating clustering for gene expression data [J].
Yeung, KY ;
Haynor, DR ;
Ruzzo, WL .
BIOINFORMATICS, 2001, 17 (04) :309-318