BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
|
2002年
/
1585卷
/
2-3期
基金:
日本科学技术振兴机构;
关键词:
phospholipase D (PLD);
apoptosis;
survival;
lipid signaling;
D O I:
10.1016/S1388-1981(02)00327-X
中图分类号:
Q5 [生物化学];
Q7 [分子生物学];
学科分类号:
071010 ;
081704 ;
摘要:
Accumulating evidence has recognized phospholipase D (PLD) as an important element in signal transduction of cell responses, including proliferation and differentiation, However, its role in pro-apoptotic, anti-apoptotic or pro-survival signaling is not well-understood. Involvement of PLD in these signaling mechanisms is considered to differ depending on the cell type and the extracellular stimulus. (C) 2002 Elsevier Science B.V. All rights reserved.