Roles of phospholipase D in apoptosis and pro-survival

被引:60
作者
Nozawa, Y [1 ]
机构
[1] Gifu Int, Dept Environm Cell Respones, Inst Biotechnol, Gifu 5050116, Japan
来源
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS | 2002年 / 1585卷 / 2-3期
基金
日本科学技术振兴机构;
关键词
phospholipase D (PLD); apoptosis; survival; lipid signaling;
D O I
10.1016/S1388-1981(02)00327-X
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Accumulating evidence has recognized phospholipase D (PLD) as an important element in signal transduction of cell responses, including proliferation and differentiation, However, its role in pro-apoptotic, anti-apoptotic or pro-survival signaling is not well-understood. Involvement of PLD in these signaling mechanisms is considered to differ depending on the cell type and the extracellular stimulus. (C) 2002 Elsevier Science B.V. All rights reserved.
引用
收藏
页码:77 / 86
页数:10
相关论文
共 110 条
[52]   PHOSPHOLIPASE-D IS PRESENT ON GOLGI-ENRICHED MEMBRANES AND ITS ACTIVATION BY ADP-RIBOSYLATION FACTOR IS SENSITIVE TO BREFELDIN-A [J].
KTISTAKIS, NT ;
BROWN, HA ;
STERNWEIS, PC ;
ROTH, MG .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1995, 92 (11) :4952-4956
[53]   Hydrogen peroxide-induced phospholipase D2 activation in lymphocytic leukemic L1210 cells [J].
Lee, BD ;
Kim, JH ;
Lee, SD ;
Kim, Y ;
Suh, PG ;
Ryu, SH .
JOURNAL OF LEUKOCYTE BIOLOGY, 2000, 67 (05) :630-636
[54]   Inhibition of phospholipase D by amphiphysins [J].
Lee, C ;
Kim, SR ;
Chung, JK ;
Frohman, MA ;
Kilimann, MW ;
Rhee, SG .
JOURNAL OF BIOLOGICAL CHEMISTRY, 2000, 275 (25) :18751-18758
[55]   Inhibition of phospholipase D by clathrin assembly protein 3 (AP3) [J].
Lee, CH ;
Kang, HS ;
Chung, JK ;
Sekiya, F ;
Kim, JR ;
Han, JS ;
Kim, SR ;
Bae, YS ;
Morris, AJ ;
Rhee, SG .
JOURNAL OF BIOLOGICAL CHEMISTRY, 1997, 272 (25) :15986-15992
[56]   Phytosphingosine and C2-phytoceramide induce cell death and inhibit carbachol-stimulated phospholipase D activation in Chinese hamster ovary cells expressing the Caenorhabditis elegans muscarinic acetylcholine receptor [J].
Lee, JS ;
Min, DS ;
Park, C ;
Park, CS ;
Cho, NJ .
FEBS LETTERS, 2001, 499 (1-2) :82-86
[57]   Actin directly interacts with phospholipase D, inhibiting its activity [J].
Lee, S ;
Park, JB ;
Kim, JH ;
Kim, Y ;
Kim, JH ;
Shin, KJ ;
Lee, JS ;
Ha, SH ;
Suh, PG ;
Ryu, SH .
JOURNAL OF BIOLOGICAL CHEMISTRY, 2001, 276 (30) :28252-28260
[58]   Phospholipase D2 activity suppresses hydrogen peroxide-induced apoptosis in PC12 cells [J].
Lee, SD ;
Lee, BD ;
Han, JM ;
Kim, JH ;
Kim, Y ;
Suh, PG ;
Ryu, SH .
JOURNAL OF NEUROCHEMISTRY, 2000, 75 (03) :1053-1059
[59]   The first crystal structure of a phospholipase D [J].
Leiros, I ;
Secundo, F ;
Zambonelli, C ;
Servi, S ;
Hough, E .
STRUCTURE, 2000, 8 (06) :655-667
[60]   PROTEIN-TYROSINE KINASE PYK2 INVOLVED IN CA2+-INDUCED REGULATION OF ION-CHANNEL AND MAP KINASE FUNCTIONS [J].
LEV, S ;
MORENO, H ;
MARTINEZ, R ;
CANOLL, P ;
PELES, E ;
MUSACCHIO, JM ;
PLOWMAN, GD ;
RUDY, B ;
SCHLESSINGER, J .
NATURE, 1995, 376 (6543) :737-745