Roles of phospholipase D in apoptosis and pro-survival

被引：60

作者：

Nozawa, Y ^{[1
]}

机构：

[1] Gifu Int, Dept Environm Cell Respones, Inst Biotechnol, Gifu 5050116, Japan

来源：

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS | 2002年 / 1585卷 / 2-3期

基金：

日本科学技术振兴机构;

关键词：

phospholipase D (PLD); apoptosis; survival; lipid signaling;

D O I：

10.1016/S1388-1981(02)00327-X

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Accumulating evidence has recognized phospholipase D (PLD) as an important element in signal transduction of cell responses, including proliferation and differentiation, However, its role in pro-apoptotic, anti-apoptotic or pro-survival signaling is not well-understood. Involvement of PLD in these signaling mechanisms is considered to differ depending on the cell type and the extracellular stimulus. (C) 2002 Elsevier Science B.V. All rights reserved.

引用

页码：77 / 86

页数：10

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