Chemical and physiologic brain imaging in schizophrenia

被引：29

作者：

McClure, RJ ^{[1
]}

Keshavan, MS ^{[1
]}

Pettegrew, JW ^{[1
]}

机构：

[1] Univ Pittsburgh, Med Ctr, Western Psychiat Inst & Clin, Dept Psychiat, Pittsburgh, PA 15213 USA

来源：

PSYCHIATRIC CLINICS OF NORTH AMERICA | 1998年 / 21卷 / 01期

关键词：

D O I：

10.1016/S0193-953X(05)70363-4

中图分类号：

R749 [精神病学];

学科分类号：

100205 ;

摘要：

Technologic advances in functional brain imaging have provided exciting and informative insights into the functional neuroanatomy and neurochemistry of schizophrenia. Using MR spectroscopy, it has been possible to examine in vivo brain metabolism and to relate observed changes to physiological processes occurring at a cellular level. Positron emission tomography and single photon emission computed tomography have revealed disturbances of cerebral blood flow and glucose metabolism in patients with schizophrenia. More recently, these tools have also proved most useful in studying the relative receptor occupancy of typical and atypical antipsychotic medications.

引用

页码：93 / +

页数：32

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