Global phylogeography of Mycobacterium tuberculosis and implications for tuberculosis product development

被引：545

作者：

Gagneux, Sebastien

Small, Peter M.

机构：

[1] Inst Syst Biol, Seattle, WA USA

[2] Bill & Melinda Gates Fdn, Seattle, WA USA

来源：

LANCET INFECTIOUS DISEASES | 2007年 / 7卷 / 05期

基金：

英国惠康基金;

关键词：

D O I：

10.1016/S1473-3099(07)70108-1

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

New tools for controlling tuberculosis are urgently needed. Despite our emerging understanding of the biogeography of Mycobacterium tuberculosis, the implications for development of new diagnostics, drugs, and vaccines is unknown. M tuberculosis has a clonal genetic population structure that is geographically constrained. Evidence suggests strain-specific differences in virulence and immunogenicity in light of this global phylogeography. We propose a strain selection framework, based on robust phylogenetic markers, which will allow for systematic and comprehensive evaluation of new tools for tuberculosis control.

引用

收藏

页码：328 / 337

页数：10

相关论文

共 145 条

[131] Pathogen adaptation under imperfect vaccination: implications for pertussis [J].

van Boven, M ;

Mooi, FR ;

Schellekens, JFP ;

de Melker, HE ;

Kretzschmar, M .

PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES, 2005, 272 (1572) :1617-1624

[132] Increased production of interleukin 4 by CD4+ and CD8+ T cells from patients with tuberculosis is related to the presence of pulmonary cavities [J].

van Crevel, R ;

Karyadi, E ;

Preyers, F ;

Leenders, M ;

Kullberg, BJ ;

Nelwan, RHH ;

van der Meer, JWM .

JOURNAL OF INFECTIOUS DISEASES, 2000, 181 (03) :1194-1197

[133] Innate immunity to Mycobacterium tuberculosis [J].

van Crevel, R ;

Ottenhoff, THM ;

van der Meer, JWM .

CLINICAL MICROBIOLOGY REVIEWS, 2002, 15 (02) :294-+

[134] DC-sign: Escape mechanism for pathogens [J].

van Kooyk, Y ;

Geijtenbeek, TBH .

NATURE REVIEWS IMMUNOLOGY, 2003, 3 (09) :697-709

[135] Changes in the Dutch Bordetella pertussis population in the first 20 years after the introduction of whole-cell vaccines [J].

van Loo, IHM ;

Mooi, FR .

MICROBIOLOGY-SGM, 2002, 148 :2011-2018

[136] Molecular epidemiology of tuberculosis and other mycobacterial infections: main methodologies and achievements [J].

van Soolingen, D .

JOURNAL OF INTERNAL MEDICINE, 2001, 249 (01) :1-26

[137] STRAIN IDENTIFICATION OF MYCOBACTERIUM-TUBERCULOSIS BY DNA FINGERPRINTING - RECOMMENDATIONS FOR A STANDARDIZED METHODOLOGY [J].

VANEMBDEN, JDA ;

CAVE, MD ;

CRAWFORD, JT ;

DALE, JW ;

EISENACH, KD ;

GICQUEL, B ;

HERMANS, P ;

MARTIN, C ;

MCADAM, R ;

SHINNICK, TM ;

SMALL, PM .

JOURNAL OF CLINICAL MICROBIOLOGY, 1993, 31 (02) :406-409

[138] PREDOMINANCE OF A SINGLE GENOTYPE OF MYCOBACTERIUM-TUBERCULOSIS IN COUNTRIES OF EAST-ASIA [J].

VANSOOLINGEN, D ;

QIAN, LS ;

DEHAAS, PEW ;

DOUGLAS, JT ;

TRAORE, H ;

PORTAELS, F ;

QING, HZ ;

ENKHSAIKAN, D ;

NYMADAWA, P ;

VANEMBDEN, JDA .

JOURNAL OF CLINICAL MICROBIOLOGY, 1995, 33 (12) :3234-3238

[139] Genetic diversity of Mycobacterium africanum clinical isolates based on IS6110-restriction fragment length polymorphism analysis, spoligotyping, and variable number of tandem DNA repeats [J].

Viana-Niero, C ;

Gutierrez, C ;

Sola, C ;

Filliol, I ;

Boulahbal, F ;

Vincent, V ;

Rastogi, N .

JOURNAL OF CLINICAL MICROBIOLOGY, 2001, 39 (01) :57-65

[140] Microevolution of the direct repeat region of Mycobacterium tuberculosis:: Implications for interpretation of spoligotyping data [J].

Warren, RM ;

Streicher, EM ;

Sampson, SL ;

van der Spuy, GD ;

Richardson, M ;

Nguyen, D ;

Behr, AA ;

Victor, TC ;

van Helden, PD .

JOURNAL OF CLINICAL MICROBIOLOGY, 2002, 40 (12) :4457-4465

← 6 7 8 9 10 11 12 13 14 15 →