Dinuclear metal complexes of Cd(II), Zn(II) and Fe(II) with triple-helical structure and predetermined chirality

被引：49

作者：

Murner, H

von Zelewsky, A

Hopfgartner, G

机构：

[1] Univ Fribourg, Inst Inorgan Chem, CH-1700 Fribourg, Switzerland

[2] F Hoffmann La Roche & Co Ltd, Div Pharma, Dept Drug Metab & Kinet, Bioanalyt Sect, CH-4002 Basel, Switzerland

[3] CALTECH, Div Chem & Chem Engn, Pasadena, CA 91125 USA

来源：

INORGANICA CHIMICA ACTA | 1998年 / 271卷 / 1-2期

关键词：

helicate complexes; self-assembly; cadmium complexes; zinc complexes; iron complexes;

D O I：

10.1016/S0020-1693(97)05890-8

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

The complex formation of members of the so-called chiragen ligand family (stereoselective linked bis-[4,5]-pineno-2,2'-bipyridines) with Cd(II), Zn(II), and Fe(II) was investigated. Using spectrophotometric titrations and electrospray MS it was determined that the major species formed in solution an complexes with an M:L=2:3 stoichiometry. Based on circular dichroism (CD) and NMR measurements, a triple helical structure with enantiomerically pure homochiral configuration at the metal centers is proposed for these dinuclear complexes. This is one of the first examples of a spontaneous self-assembly process leading to a dinuclear triple-helicate with pronounced preference for the formation of one of the possible stereoisomers. (C) 1998 Elsevier Science S.A.

引用

页码：36 / 39

页数：4

共 23 条

[1] Self-assembly of a triple-stranded meso-helicate from two iron(II) ions and three [CH2](3)-bridged bis(2,2'-bipyridine) ligands [J].