Stress-induced structural transitions in DNA and proteins

被引:78
作者
Strick, TR
Allemand, JF
Bensimon, D
Croquette, V
机构
[1] Ecole Normale Super, LPS, CNRS, UMR 8550, F-75231 Paris 05, France
[2] Ecole Normale Super, PASTEUR, CNRS, UMR 8640, F-75231 Paris, France
来源
ANNUAL REVIEW OF BIOPHYSICS AND BIOMOLECULAR STRUCTURE | 2000年 / 29卷
关键词
single molecule manipulation; DNA unzipping; protein folding;
D O I
10.1146/annurev.biophys.29.1.523
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The ability to manipulate, stretch and twist biomolecules opens the way to an understanding of their structural transitions. We review some of the recently discovered stress-induced structural transitions in DNA as well as the application of single molecule manipulation techniques to DNA unzipping and to the study of protein folding/unfolding transitions.
引用
收藏
页码:523 / 543
页数:21
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