Imaging the Human Medial Temporal Lobe with High-Resolution fMRI

被引:137
作者
Carr, Valerie A. [1 ]
Rissman, Jesse [1 ]
Wagner, Anthony D. [1 ,2 ]
机构
[1] Stanford Univ, Dept Psychol, Stanford, CA 94305 USA
[2] Stanford Univ, Neurosci Program, Stanford, CA 94305 USA
关键词
COMPLEMENTARY-LEARNING-SYSTEMS; LONG-TERM-MEMORY; VOXEL PATTERN-ANALYSIS; VISUAL WORKING-MEMORY; MATCH-TO-SAMPLE; RECOGNITION MEMORY; PERIRHINAL CORTEX; HIPPOCAMPAL FUNCTION; EPISODIC MEMORY; FUNCTIONAL MRI;
D O I
10.1016/j.neuron.2009.12.022
中图分类号
Q189 [神经科学];
学科分类号
071006 [神经生物学];
摘要
High-resolution functional MRI (hr-fMRI) affords unique leverage on the functional properties of human medial temporal lobe (MTL) substructures. We review initial hr-fMRI efforts to delineate (1) encoding and retrieval processes within the hippocampal circuit, (2) hippocampal subfield contributions to pattern separation and pattern completion, and (3) the representational capabilities of distinct MTL subregions. Extant data reveal functional heterogeneity within human MTL and highlight the promise of hr-fMRI for bridging human, animal, and computational approaches to understanding MTL function.
引用
收藏
页码:298 / 308
页数:11
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