Novel antibacterial fibers of quaternized chitosan and poly(vinyl pyrrolidone) prepared by electrospinning

被引：215

作者：

Ignatova, Milena ^{[1
]}

Manolova, Nevena ^{[1
]}

Rashkov, Iliya ^{[1
]}

机构：

[1] Bulgarian Acad Sci, Inst Polymers, Lab Bioact Polymers, BU-1113 Sofia, Bulgaria

来源：

EUROPEAN POLYMER JOURNAL | 2007年 / 43卷 / 04期

关键词：

electrospinning; water-resistant electrospun fibers; quaternized chitosan; poly(vinyl pyrrolidone); photo-crosslinking; antibacterial activity;

D O I：

10.1016/j.eurpolymj.2007.01.012

中图分类号：

O63 [高分子化学（高聚物）];

学科分类号：

070305 ; 080501 ; 081704 ;

摘要：

The preparation of continuous defect-free fibers from quaternized chitosan derivative (QCh) has been achieved by electrospinning of mixed aqueous solutions of QCh with poly(vinyl pyrrolidone) (PVP). The average fiber diameter significantly decreases from 2800 to 1500 nm on increasing the polyelectrolyte content. In order to impart to QCh/PVP electrospun fibers stability to water and water vapor, the fibers have been crosslinked by incorporation of photo-crosslinking additives into QCh/PVP spinning solutions and subsequent UV irradiation of the electrospun fibers. Photo-crosslinked QCh-containing electrospun mats show high antibacterial activity against the Grain-positive bacteria Staphylococcus aureus and Gram-negative bacteria Escherichia coli. (C) 2007 Elsevier Ltd. All rights reserved.

引用

页码：1112 / 1122

页数：11

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