We know you are in there: Conversing with the indigenous gut microbiota

被引：68

作者：

Cheesman, Sarah E. ^{[1
]}

Guillemin, Karen ^{[1
]}

机构：

[1] Univ Oregon, Inst Mol Biol, Eugene, OR 97403 USA

来源：

RESEARCH IN MICROBIOLOGY | 2007年 / 158卷 / 01期

关键词：

microbiota; vertebrate gut; mutualism; microbial-associated molecular patterns; epithelial homeostasis; innate immunity; glycans;

D O I：

10.1016/j.resmic.2006.10.005

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The vertebrate gut harbors a coevolved consortium of microbes that plays critical roles in the development and health of this organ. Here we discuss recent insights into the microbial-host molecular dialogs that shape the digestive tracts of the model vertebrates, mice and zebrafish, and consider the parallels between vertebrate-microbial mutualisms and the well-studied squid-Vibrio symbiosis. (c) 2006 Elsevier Masson SAS. All fights reserved.

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页码：2 / 9

页数：8

相关论文

共 44 条

[1] TLR signaling in the gut in health and disease [J].

Abreu, MT ;

Fukata, M ;

Arditi, M .

JOURNAL OF IMMUNOLOGY, 2005, 174 (08) :4453-4460

[2] Host-bacterial mutualism in the human intestine [J].

Bäckhed, F ;

Ley, RE ;

Sonnenburg, JL ;

Peterson, DA ;

Gordon, JI .

SCIENCE, 2005, 307 (5717) :1915-1920

[3] Distinct signals from the microbiota promote different aspects of zebrafish gut differentiation [J].

Bates, Jennifer M. ;

Mittge, Erika ;

Kuhlman, Julie ;

Baden, Katrina N. ;

Cheesman, Sarah E. ;

Guillemin, Karen .

DEVELOPMENTAL BIOLOGY, 2006, 297 (02) :374-386

[4] Intestinal epithelial TOLLerance versus inTOLLerance of commensals [J].

Cario, E ;

Podolsky, DK .

MOLECULAR IMMUNOLOGY, 2005, 42 (08) :887-893

[5] Symbiotic bacteria direct expression of an intestinal bactericidal lectin [J].

Cash, Heather L. ;

Whitham, Cecilia V. ;

Behrendt, Cassie L. ;

Hooper, Lora V. .

SCIENCE, 2006, 313 (5790) :1126-1130

[6] TLRs regulate the gatekeeping functions of the intestinal follicle-associated epithelium [J].

Chabot, Sophie ;

Wagner, Jessica S. ;

Farrant, Stephanie ;

Neutra, Marian R. .

JOURNAL OF IMMUNOLOGY, 2006, 176 (07) :4275-4283

[7] Breaching the great wall: peptidoglycan and microbial interactions [J].

Cloud-Hansen, Karen A. ;

Peterson, S. Brook ;

Stabb, Eric V. ;

Goldman, William E. ;

McFall-Ngai, Margaret J. ;

Handelsman, Jo .

NATURE REVIEWS MICROBIOLOGY, 2006, 4 (09) :710-716

[8] Molecular interactions between bacterial symbionts and their hosts [J].

Dale, Colin ;

Moran, Nancy A. .

CELL, 2006, 126 (03) :453-465

[9] Assembly of the human intestinal microbiota [J].

Dethlefsen, Les ;

Eckburg, Paul B. ;

Bik, Elisabeth M. ;

Relman, David A. .

TRENDS IN ECOLOGY & EVOLUTION, 2006, 21 (09) :517-523

[10] Indigenous microbes and their soluble factors differentially modulate intestinal glycosylation steps in vivo - Use of a "lectin assay'' to survey in vivo glycosylation changes [J].

Freitas, M ;

Axelsson, LG ;

Cayuela, C ;

Midtvedt, T ;

Trugnan, G .

HISTOCHEMISTRY AND CELL BIOLOGY, 2005, 124 (05) :423-433

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