Comparison of tafenoquine (WR238605) and primaquine in the post-exposure (terminal) prophylaxis of vivax malaria) in Australian Defence Force personnel

被引:37
作者
Nasveld, P [1 ]
Kitchener, S
Edstein, M
Rieckmann, K
机构
[1] Australian Def Force Combined Hlth Element, Loloho, North Solomons, Papua N Guinea
[2] Australian Army Malaria Inst, Gallipoli Barracks, Qld 4051, Australia
关键词
malaria; Plasmodium vivax; chemotherapy; tafenoquine; primaquine; Bougainville Island;
D O I
10.1016/S0035-9203(02)90351-2
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
On return from duty in North Solomons Province (including Bougainville Island), Papua New Guinea, 586 Australian Defence Force personnel received either primaquine (14-d) or tafenoquine (3-d) post-exposure malaria prophylaxis. Within 12 months, 6 of the 214 volunteers receiving primaquine and 7 of 378 receiving tafenoquine had developed vivax malaria. Overall, volunteers preferred the shorter course of tafenoquine.
引用
收藏
页码:683 / 684
页数:2
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