Transcriptional control of cell type and morphogenesis in Candida albicans

被引:68
作者
Whiteway, M
机构
[1] Natl Res Council Canada, Biotechnol Res Inst, Montreal, PQ H4P 2R2, Canada
[2] McGill Univ, Dept Biol, Montreal, PQ H3A 1B1, Canada
关键词
D O I
10.1016/S1369-5274(00)00144-2
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Candida albicans has a number of transcriptional regulatory circuits that control aspects of cell type and cell morphogenesis. Recent work has uncovered a cryptic mating-type locus, and a variety of transcription factors that are important in regulation of the transition from yeast growth to hypha[ growth. In some cases, the signalling pathways regulating these transcription factors are becoming defined. Analysis of phenotypic switching implicates internal factors, as well as external signals, in control of cellular morphogenesis.
引用
收藏
页码:582 / 588
页数:7
相关论文
共 54 条
[1]   COS1, a two-component histidine kinase that is involved in hyphal development in the opportunistic pathogen Candida albicans [J].
Alex, LA ;
Korch, C ;
Selitrennikoff, CP ;
Simon, MI .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1998, 95 (12) :7069-7073
[2]   Signalling in the yeasts: An informational cascade with links to the filamentous fungi [J].
Banuett, F .
MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS, 1998, 62 (02) :249-+
[3]  
Braun BR, 2000, GENETICS, V155, P57
[4]   Control of filament formation in Candida albicans by the transcriptional repressor TUP1 [J].
Braun, BR ;
Johnson, AD .
SCIENCE, 1997, 277 (5322) :105-109
[5]   Regulatory networks controlling Candida albicans morphogenesis [J].
Brown, AJP ;
Gow, NAR .
TRENDS IN MICROBIOLOGY, 1999, 7 (08) :333-338
[6]   Filamentous growth of Candida albicans in response to physical environmental cues and its regulation by the unique CZF1 gene [J].
Brown, DH ;
Giusani, AD ;
Chen, X ;
Kumamoto, CA .
MOLECULAR MICROBIOLOGY, 1999, 34 (04) :651-662
[7]  
Calera JA, 1998, YEAST, V14, P665, DOI 10.1002/(SICI)1097-0061(199805)14:7&lt
[8]  
665::AID-YEA246&gt
[9]  
3.0.CO
[10]  
2-#