Protein degradation: Recognition of ubiquitinylated substrates

被引：33

作者：

Hartmann-Petersen, R

Gordon, C

机构：

[1] Univ Copenhagen, August Krogh Inst, DK-2100 Copenhagen, Denmark

[2] Western Gen Hosp, MRC, Human Genet Unit, Edinburgh EH4 2XU, Midlothian, Scotland

来源：

CURRENT BIOLOGY | 2004年 / 14卷 / 18期

关键词：

D O I：

10.1016/j.cub.2004.09.012

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A cell-free system has been developed in budding yeast that provides direct evidence that the Dsk2/Dph1, Rad23/Rhp23 and Rpn10/Pus1 multiubiquitin-binding proteins, long implicated in substrate recognition and presentation to the 26S proteasome, actually fulfil such a role.

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收藏

页码：R754 / R756

页数：3

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