Lymphoma in Sjogren's syndrome - From histopathology to molecular pathology

被引：23

作者：

Jordan, RCK

Speight, PM

机构：

[1] UCL EASTMAN DENT INST ORAL HLTH CARE SCI, DEPT ORAL PATHOL, LONDON WC1X 8LD, ENGLAND

[2] SUNNYBROOK HLTH SCI CTR, TORONTO, ON M4N 3M5, CANADA

[3] UNIV TORONTO, TORONTO, ON, CANADA

来源：

ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY AND ENDODONTOLOGY | 1996年 / 81卷 / 03期

基金：

英国医学研究理事会;

关键词：

D O I：

10.1016/S1079-2104(96)80331-3

中图分类号：

R78 [口腔科学];

学科分类号：

1003 ;

摘要：

A number of autoimmune diseases predispose to the development of neoplasia. A particularly well-recognized association is the development of lymphoma in Sjogren's syndrome. Although this risk has been estimated to be 44 times that of the general population; few reliable prognostic indexes exist for individual patients. Recent advances in molecular biology have improved our understanding of Sjogren's syndrome and permitted better characterization of the generalized lymphoproliferation associated with the condition. This article reviews the histopathology of the major and minor salivary gland lesions of Sjogren's syndrome and discusses advances in molecular biology that have permitted more accurate prediction of lymphoma development in this group of patients.

引用

页码：308 / 320

页数：13

共 74 条

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