The centrifugal microfluidic bio-disk platform

被引：333

作者：

Ducree, Jens

Haeberle, Stefan

Lutz, Sascha

Pausch, Sarah

von Stetten, Felix

Zengerle, Roland

机构：

[1] HSG IMIT, D-78052 Villingen Schwenningen, Germany

[2] IMTEK, Dept Microsyst Engn, D-79110 Freiburg, Germany

来源：

JOURNAL OF MICROMECHANICS AND MICROENGINEERING | 2007年 / 17卷 / 07期

关键词：

D O I：

10.1088/0960-1317/17/7/S07

中图分类号：

TM [电工技术]; TN [电子技术、通信技术];

学科分类号：

0808 ; 0809 ;

摘要：

This paper reviews the centrifugal 'Bio-Disk' platform which is based on rotationally controlled, multi-scale liquid handling to fully integrate and automate complex analysis and synthesis protocols in the life sciences. The platform offers the crucial ingredients for a rapid development of applications: a coherent library of fluidic unit operations, a device technology for actuation, liquid interfacing and detection as well as a developer toolbox providing experimental testing, rapid prototyping and simulation capabilities. Various applications in the fields of life science, in vitro diagnostics and micro-process engineering are demonstrated.

引用

收藏

页码：S103 / S115

页数：13

相关论文

共 66 条

[41] Lab on a CD [J].

Madou, Marc ;

Zoval, Jim ;

Jia, Guangyao ;

Kido, Horacio ;

Kim, Jitae ;

Kim, Nahui .

ANNUAL REVIEW OF BIOMEDICAL ENGINEERING, 2006, 8 :601-628

[42] The LabCD™:: A centrifuge-based microfluidic platform for diagnostics [J].

Madou, MJ ;

Kellogg, GJ .

SYSTEMS AND TECHNOLOGIES FOR CLINICAL DIAGNOSTICS AND DRUG DISCOVERY, PROCEEDINGS OF, 1998, 3259 :80-93

[43]

McDonald JC, 2000, ELECTROPHORESIS, V21, P27, DOI 10.1002/(SICI)1522-2683(20000101)21:1<27::AID-ELPS27>3.0.CO

[44]

2-C

[45] Hydrophobic microfluidics [J].

McNeely, MR ;

Spute, MK ;

Tusneem, NA ;

Oliphant, AR .

MICROFLUIDIC DEVICES AND SYSTEMS II, 1999, 3877 :210-220

[46] An externally driven magnetic microstirrer [J].

Mensing, GA ;

Pearce, TM ;

Graham, MD ;

Beebe, DJ .

PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY A-MATHEMATICAL PHYSICAL AND ENGINEERING SCIENCES, 2004, 362 (1818) :1059-1068

[47] LIGA and related technologies for industrial application [J].

Menz, W .

SENSORS AND ACTUATORS A-PHYSICAL, 1996, 54 (1-3) :785-789

[48] Micromixers - a review [J].

Nguyen, NT ;

Wu, ZG .

JOURNAL OF MICROMECHANICS AND MICROENGINEERING, 2005, 15 (02) :R1-R16

[49] Microfluidic tool box as technology platform for hand-held diagnostics [J].

Pugia, MJ ;

Blankenstein, G ;

Peters, RP ;

Profitt, JA ;

Kadel, K ;

Willms, T ;

Sommer, R ;

Kuo, HH ;

Schulman, LS .

CLINICAL CHEMISTRY, 2005, 51 (10) :1923-1932

[50] Ac electrokinetics: a review of forces in microelectrode structures [J].

Ramos, A ;

Morgan, H ;

Green, NG ;

Castellanos, A .

JOURNAL OF PHYSICS D-APPLIED PHYSICS, 1998, 31 (18) :2338-2353

← 1 2 3 4 5 6 7 →