Antifungal drug susceptibility profile of Pichia anomala isolates from patients presenting with nosocomial fungemia

被引:23
作者
Ribeiro da Matta, Vania Lucia
Melhem, Marcia de Souza Carvalho
Colombo, Arnaldo Lopes
Moretti, Maria Luiza
Rodero, Laura
Duboc de Almeida, Gisele Madeira
Martins, Marilena dos Anjos
Costa, Silvia Figueiredo
Dias, Maria Beatriz G. Souza
Nucci, Marcio
Levin, Anna S.
机构
[1] Adolfo Lutz Inst, Sao Paulo, Brazil
[2] Univ Fed Sao Paulo, Div Infect Dis, Sao Paulo, Brazil
[3] Univ Estadual Campinas, Fac Med Sci, Div Infect Dis, Campinas, SP, Brazil
[4] Univ Catolica Argentina, Fac Med, Buenos Aires, DF, Argentina
[5] Univ Sao Paulo, Hosp Clin, Lab Clin Micorbiol, Sao Paulo, Brazil
[6] Univ Sao Paulo, Hosp Clin, Hosp Infect Control Dept, LIM 54, Sao Paulo, Brazil
[7] Hosp Sirio Libanes, Sao Paulo, Brazil
[8] Univ Fed Rio de Janeiro, Dept Internal Med, Rio De Janeiro, Brazil
[9] Univ Sao Paulo, Hosp Clin, Dept Infect Dis, Sao Paulo, Brazil
关键词
D O I
10.1128/AAC.01038-06
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
In vitro susceptibility of 58 isolates of Pichia anomala to five antifungal drugs using two broth microdilution methods (CLSI and EUCAST) was analyzed. Low susceptibility to itraconazole was observed. Fluconazole, voriconazole, amphotericin B, and caspofungin showed good antifungal activity, although relatively high drug concentrations were necessary to inhibit the isolates.
引用
收藏
页码:1573 / 1576
页数:4
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