Antifungal drug susceptibility profile of Pichia anomala isolates from patients presenting with nosocomial fungemia

被引:23
作者
Ribeiro da Matta, Vania Lucia
Melhem, Marcia de Souza Carvalho
Colombo, Arnaldo Lopes
Moretti, Maria Luiza
Rodero, Laura
Duboc de Almeida, Gisele Madeira
Martins, Marilena dos Anjos
Costa, Silvia Figueiredo
Dias, Maria Beatriz G. Souza
Nucci, Marcio
Levin, Anna S.
机构
[1] Adolfo Lutz Inst, Sao Paulo, Brazil
[2] Univ Fed Sao Paulo, Div Infect Dis, Sao Paulo, Brazil
[3] Univ Estadual Campinas, Fac Med Sci, Div Infect Dis, Campinas, SP, Brazil
[4] Univ Catolica Argentina, Fac Med, Buenos Aires, DF, Argentina
[5] Univ Sao Paulo, Hosp Clin, Lab Clin Micorbiol, Sao Paulo, Brazil
[6] Univ Sao Paulo, Hosp Clin, Hosp Infect Control Dept, LIM 54, Sao Paulo, Brazil
[7] Hosp Sirio Libanes, Sao Paulo, Brazil
[8] Univ Fed Rio de Janeiro, Dept Internal Med, Rio De Janeiro, Brazil
[9] Univ Sao Paulo, Hosp Clin, Dept Infect Dis, Sao Paulo, Brazil
关键词
D O I
10.1128/AAC.01038-06
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
In vitro susceptibility of 58 isolates of Pichia anomala to five antifungal drugs using two broth microdilution methods (CLSI and EUCAST) was analyzed. Low susceptibility to itraconazole was observed. Fluconazole, voriconazole, amphotericin B, and caspofungin showed good antifungal activity, although relatively high drug concentrations were necessary to inhibit the isolates.
引用
收藏
页码:1573 / 1576
页数:4
相关论文
共 43 条
[21]  
*NCCLS CLSI, 2002, M27A2 NCCLS CLSI
[22]   Do in vitro susceptibility data predict the microbiologic response to amphotericin B?: Results of a prospective study of patients with Candida fungemia [J].
Nguyen, MH ;
Clancy, CJ ;
Yu, VL ;
Yu, YC ;
Morris, AJ ;
Snydman, DR ;
Sutton, DA ;
Rinaldi, MG .
JOURNAL OF INFECTIOUS DISEASES, 1998, 177 (02) :425-430
[23]   INFECTIVE ENDOCARDITIS OF A BICUSPID AORTIC-VALVE CAUSED BY HANSENULA ANOMALA [J].
NOHINEK, B ;
ZEECHENG, CS ;
BARNES, WG ;
DALL, L ;
GIBBS, HR .
AMERICAN JOURNAL OF MEDICINE, 1987, 82 (01) :165-168
[24]   Interlaboratory comparison of results of susceptibility testing with caspofungin against Candida and Aspergillus species [J].
Odds, FC ;
Motyl, M ;
Andrade, R ;
Bille, J ;
Cantón, E ;
Cuenca-Estrella, M ;
Davidson, A ;
Durussel, C ;
Ellis, D ;
Foraker, E ;
Fothergill, AW ;
Ghannoum, MA ;
Giacobbe, RA ;
Gobernado, M ;
Handke, R ;
Laverdière, M ;
Lee-Yang, W ;
Merz, WG ;
Ostrosky-Zeichner, L ;
Pemán, J ;
Perea, S ;
Perfect, JR ;
Pfaller, MA ;
Proia, L ;
Rex, JH ;
Rinaldi, MG ;
Rodriguez-Tudela, JL ;
Schell, WA ;
Shields, C ;
Sutton, DA ;
Verweij, PE ;
Warnock, DW .
JOURNAL OF CLINICAL MICROBIOLOGY, 2004, 42 (08) :3475-3482
[25]   Antifungal susceptibility survey of 2,000 bloodstream Candida isolates in the United States [J].
Ostrosky-Zeichner, L ;
Rex, JH ;
Pappas, PG ;
Hamill, RJ ;
Larsen, RA ;
Horowitz, HW ;
Powderly, WG ;
Hyslop, N ;
Kauffman, CA ;
Cleary, J ;
Mangino, JE ;
Lee, J .
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2003, 47 (10) :3149-3154
[26]   An outbreak of Pichia anomala fungemia in a Brazilian pediatric intensive care unit [J].
Pasqualotto, AC ;
Sukiennik, TCT ;
Severo, LC ;
de Amorim, CS ;
Colombo, AL .
INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY, 2005, 26 (06) :553-558
[27]   Correlation of MIC with outcome for Candida species tested against voriconazole:: Analysis and proposal for interpretive breakpoints [J].
Pfaller, MA ;
Diekema, DJ ;
Rex, JH ;
Espinel-Ingroff, A ;
Johnson, EM ;
Andes, D ;
Chaturvedi, V ;
Ghannoum, MA ;
Odds, FC ;
Rinaldi, MG ;
Sheehan, DJ ;
Troke, P ;
Walsh, TJ ;
Warnock, DW .
JOURNAL OF CLINICAL MICROBIOLOGY, 2006, 44 (03) :819-826
[28]   Further standardization of broth microdilution methodology for in vitro susceptibility testing of caspofungin against Candida species by use of an international collection of more than 3,000 clinical isolates [J].
Pfaller, MA ;
Messer, SA ;
Boyken, L ;
Rice, C ;
Tendolkar, S ;
Hollis, RJ ;
Diekema, DJ .
JOURNAL OF CLINICAL MICROBIOLOGY, 2004, 42 (07) :3117-3119
[29]   In vitro activities of voriconazole, posaconazole, and fluconazole against 4,169 clinical isolates of Candida spp. and Cryptococcus neoformans collected during 2001 and 2002 in the ARTEMIS global antifungal surveillance program [J].
Pfaller, MA ;
Messer, SA ;
Boyken, L ;
Hollis, RJ ;
Rice, C ;
Tendolkar, S ;
Diekema, DJ .
DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE, 2004, 48 (03) :201-205
[30]   In vitro susceptibilities of rare Candida bloodstream isolates to ravuconazole and three comparative antifungal agents [J].
Pfaller, MA ;
Diekema, DJ ;
Messer, SA ;
Boyken, L ;
Hollis, RJ ;
Jones, RN .
DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE, 2004, 48 (02) :101-105