Near-infrared fluorescence imaging with water-soluble lead salt quantum dots

被引:116
作者
Hyun, Byung-Ryool [1 ]
Chen, Hongyu
Rey, Diego A.
Wise, Frank W.
Batt, Carl A.
机构
[1] Cornell Univ, Dept Food Sci, Ithaca, NY 14853 USA
[2] Cornell Univ, Dept Biomed Engn, Ithaca, NY 14853 USA
[3] Cornell Univ, Sch Appl & Engn Phys, Ithaca, NY 14853 USA
关键词
D O I
10.1021/jp068455j
中图分类号
O64 [物理化学(理论化学)、化学物理学];
学科分类号
070304 ; 081704 ;
摘要
A simple procedure for transferring PbS and PbSe quantum dots into water is presented, along with characterization of the resulting water-soluble quantum dots. The external surface of the water-soluble quantum dots include carboxylic groups, which will allow target-specific labeling of cells. As a first example, near-infrared fluorescence imaging of human colon cancer cells is demonstrated using these water-soluble near-infrared fluorophores.
引用
收藏
页码:5726 / 5730
页数:5
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