A triazole-templated ring-closing metathesis for constructing novel fused and bridged triazoles

被引：97

作者：

Zhang, Xuejun

Hsung, Richard P.

Li, Hongyan

机构：

[1] Univ Wisconsin, Div Pharmaceut Sci, Madison, WI 53705 USA

[2] Univ Wisconsin, Dept Chem, Madison, WI 53705 USA

来源：

CHEMICAL COMMUNICATIONS | 2007年 / 23期

关键词：

D O I：

10.1039/b701040k

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The feasibility of trapping the vinyl copper intermediate generated in situ from azide-[3 + 2] cycloadditions and viability of employing these triazoles as unique templates for ring-closing metathesis are described here; this work effectively combines the two powerful reactions for the first time to construct various de novo fused and bridged triazoles that are otherwise not trivial to synthesize.

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收藏

页码：2420 / 2422

页数：3

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