Universal gradient substrates for "click" biofunctionalization

被引：102

作者：

Gallant, Nathan D. ^{[1
]}

Lavery, Kristopher A. ^{[1
]}

Amis, Eric J. ^{[1
]}

Becker, Matthew L. ^{[1
]}

机构：

[1] Natl Inst Stand & Technol, Polymers Div, Gaithersburg, MD 20899 USA

来源：

ADVANCED MATERIALS | 2007年 / 19卷 / 07期

关键词：

D O I：

10.1002/adma.200602221

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Versatile templates for gradient immobilization of biomolecules by click chemistry are easily generated from reproducible and tunable surface energy gradients. An arginine-glycine-aspartate (RGD) peptide density gradient controls cell adhesion (see figure), and demonstrates the utility of this fabrication process for making substrates that can screen cell response to bioactive materials.

引用

页码：965 / +

页数：6

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