Selective, orally active 5-HT1D receptor agonists as potential antimigraine agents

被引：21

作者：

MacLeod, AM

Street, LJ

Reeve, AJ

Jelley, RA

Sternfeld, F

Beer, MS

Stanton, JA

Watt, AP

Rathbone, D

Matassa, VG

机构：

[1] MERCK SHARP & DOHME LTD,RES LABS,NEUROSCI RES CTR,DEPT BIOCHEM,HARLOW CM20 2QR,ESSEX,ENGLAND

[2] MERCK SHARP & DOHME LTD,RES LABS,NEUROSCI RES CTR,DEPT BIOANALYT,HARLOW CM20 2QR,ESSEX,ENGLAND

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1997年 / 40卷 / 22期

关键词：

D O I：

10.1021/jm9704560

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

[No abstract available]

引用

页码：3501 / 3503

页数：3

共 19 条

[1] CLONING OF ANOTHER HUMAN SEROTONIN RECEPTOR (5-HT1F) - A 5TH 5-HT1 RECEPTOR SUBTYPE COUPLED TO THE INHIBITION OF ADENYLATE-CYCLASE [J].

ADHAM, N ;

KAO, HT ;

SCHECHTER, LE ;

BARD, J ;

OLSEN, M ;

URQUHART, D ;

DURKIN, M ;

HARTIG, PR ;

WEINSHANK, RL ;

BRANCHEK, TA .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1993, 90 (02) :408-412

[2]

AUDIA JE, Patent No. 705600

[3]

Bouchelet I, 1996, MOL PHARMACOL, V50, P219

[4] NEUROGENIC MODEL OF MIGRAINE [J].

BUZZI, MG ;

BONAMINI, M ;

MOSKOWITZ, MA .

CEPHALALGIA, 1995, 15 (04) :277-280

[5] 3-[2-(pyrrolidin-1-yl)ethyl]indoles and 3-[3-(piperidin-1-yl)propyl]indoles: Agonists for the h5-HT1D receptor with high selectivity over the h5-HT1B subtype [J].

Castro, JL ;

Street, LJ ;

Guiblin, AR ;

Jelley, RA ;

Russell, MGN ;

Sternfeld, F ;

Beer, MS ;

Stanton, JA ;

Matassa, VG .

JOURNAL OF MEDICINAL CHEMISTRY, 1997, 40 (22) :3497-3500

[6] A COMPARISON OF THE CONTRACTILE EFFECTS OF 5-HYDROXYTRYPTAMINE, SUMATRIPTAN AND MK-462 ON HUMAN CORONARY-ARTERY IN-VITRO [J].

FERRO, A ;

LONGMORE, J ;

HILL, RG ;

BROWN, MJ .

BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 1995, 40 (03) :245-251

[7]

HAMEL E, 1996, SEROTONIN ID RES ALE, V1, P19

[8] 5-HT receptor classification and nomenclature: Towards a harmonization with the human genome [J].

Hoyer, D ;

Martin, G .

NEUROPHARMACOLOGY, 1997, 36 (4-5) :419-428

[9] CLASSIFICATION AND NOMENCLATURE OF SOMATOSTATIN RECEPTORS [J].

HOYER, D ;

BELL, GI ;

BERELOWITZ, M ;

EPELBAUM, J ;

FENIUK, W ;

HUMPHREY, PPA ;

OCARROLL, AM ;

PATEL, YC ;

SCHONBRUNN, A ;

TAYLOR, JE ;

REISINE, T .

TRENDS IN PHARMACOLOGICAL SCIENCES, 1995, 16 (03) :86-88

[10] THE MODE OF ACTION OF SUMATRIPTAN IS VASCULAR - A DEBATE [J].

HUMPHREY, PPA ;

GOADSBY, PJ .

CEPHALALGIA, 1994, 14 (06) :401-410

← 1 2 →