Gold-catalyzed efficient preparation of linear α-iodoenones from propargylic acetates

被引：152

作者：

Yu, Meng ^{[1
]}

Zhang, Guozhu ^{[1
]}

Zhang, Liming ^{[1
]}

机构：

[1] Univ Nevada, Dept Chem, Reno, NV 89557 USA

来源：

ORGANIC LETTERS | 2007年 / 9卷 / 11期

关键词：

D O I：

10.1021/ol070637o

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Only 2 mol % of Au( PPh3) NTf2 is needed to convert readily accessible propargylic acetates into versatile linear alpha-iodoenones in good to excellent yields. This reaction is easy to execute and has broad substrate scope. Good to excellent Z-selectivities are observed in the cases of aliphatic propargylic acetates derived from aldehydes.

引用

页码：2147 / 2150

页数：4

共 43 条

[41] Efficient synthesis of cyclopentenones from enynyl acetates via tandem Au(I)-catalyzed 3,3-rearrangement and the Nazarov reaction [J].