Two new gene cassettes, drf17 (for trimethoprim resistance) and aadA4 (for spectinomycin/streptomycin resistance), inserted in an Escherichia coli class 1 integron

被引：14

作者：

Chang, CY ^{[1
]}

Chang, LL ^{[1
]}

Chang, YH ^{[1
]}

Lee, TM ^{[1
]}

Li, YH ^{[1
]}

Chang, SF ^{[1
]}

机构：

[1] Kaohsiung Med Univ, Sch Med, Dept Microbiol, Kaohsiung 807, Taiwan

来源：

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY | 2000年 / 46卷 / 01期

关键词：

D O I：

10.1093/jac/46.1.87

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

Two new gene cassettes, dfr17 and aadA4, inserted in a class 1 integron of Escherichia coli EC107, are described here. The dfr17 cassette encodes trimethoprim resistance and has 91% identity with the dfrVII dihydrofolate reductase gene. The aadA4 cassette confers resistance to spectinomycin and streptomycin and shows 94% identity with the aadA3 gene. The integron carrying the dfr17 and aadA4 cassettes was located on a conjugative plasmid, pEC1072.

引用

页码：87 / 89

页数：3

共 10 条

[1] New trimethoprim-resistant dihydrofolate reductase cassette, dfrXV, inserted in a class 1 integron [J].

Adrian, PV ;

du Plessis, M ;

Klugman, KP ;

Amyes, SGB .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1998, 42 (09) :2221-2224

[2]

[Anonymous], 1993, M7A3 NCCLS

[3] Plasmid pDGO100 contains a second integron with the trimethoprim resistance gene dfrA7 as the inserted cassette [J].

Burnside, JM ;

Obbink, DJG .

PLASMID, 1996, 35 (01) :67-70

[4] TRIMETHOPRIM AND SULFONAMIDE RESISTANCE [J].

HUOVINEN, P ;

SUNDSTROM, L ;

SWEDBERG, G ;

SKOLD, O .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1995, 39 (02) :279-289

[5] RAPID PROCEDURE FOR DETECTION AND ISOLATION OF LARGE AND SMALL PLASMIDS [J].

KADO, CI ;

LIU, ST .

JOURNAL OF BACTERIOLOGY, 1981, 145 (03) :1365-1373

[6] DIVERSITY AND RELATIVE STRENGTH OF TANDEM PROMOTERS FOR THE ANTIBIOTIC-RESISTANCE GENES OF SEVERAL INTEGRONS [J].

LEVESQUE, C ;

BRASSARD, S ;

LAPOINTE, J ;

ROY, PH .

GENE, 1994, 142 (01) :49-54

[7] PCR MAPPING OF INTEGRONS REVEALS SEVERAL NOVEL COMBINATIONS OF RESISTANCE GENES [J].

LEVESQUE, C ;

PICHE, L ;

LAROSE, C ;

ROY, PH .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1995, 39 (01) :185-191

[8]

National Committee for Clinical Laboratory Standards, 1993, M2A5 NCCLS

[9] Gene cassettes: A new class of mobile element [J].

Recchia, GD ;

Hall, RM .

MICROBIOLOGY-UK, 1995, 141 :3015-3027

[10] CLONING AND CHARACTERIZATION OF A 3-N-AMINOGLYCOSIDE ACETYLTRANSFERASE GENE, AAC(3)-IB, FROM PSEUDOMONAS-AERUGINOSA [J].

SCHWOCHO, LR ;

SCHAFFNER, CP ;

MILLER, GH ;

HARE, RS ;

SHAW, KJ .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1995, 39 (08) :1790-1796

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