Tuneable DNA-based asymmetric catalysis using a G-quadruplex supramolecular assembly

被引：88

作者：

Roe, Stephen ^{[1
]}

Ritson, Dougal J. ^{[1
]}

Garner, Tom ^{[1
]}

Searle, Mark ^{[1
]}

Moses, John E. ^{[1
]}

机构：

[1] Univ Nottingham, Sch Chem, Nottingham NG7 2RD, England

来源：

CHEMICAL COMMUNICATIONS | 2010年 / 46卷 / 24期

基金：

英国工程与自然科学研究理事会;

关键词：

D O I：

10.1039/c0cc00194e

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Described is the first modular construction of a G-quadruplex chiral catalyst. The key objective was to use G-quadruplex structures to act as chiral ligands that would allow access to either enantiomer of the product of a Diels-Alder reaction.

引用

页码：4309 / 4311

页数：3

共 18 条

[1]

Balasubramanian S, 2006, RSC BIOMOL SCI, pV

[2] Repression of Translation of Human Estrogen Receptor α by G-Quadruplex Formation [J].

Balkwill, Graham D. ;

Derecka, Kamila ;

Garner, Thomas P. ;

Hodgman, Charlie ;

Flint, Anthony P. F. ;

Searle, Mark S. .

BIOCHEMISTRY, 2009, 48 (48) :11487-11495

[3] DNA-based asymmetric catalysis: Sequence-dependent rate acceleration and enantioselectivity [J].

Boersma, Arnold J. ;

Klijn, Jaap E. ;

Feringa, Ben L. ;

Roelfes, Gerard .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2008, 130 (35) :11783-11790

[4] Enantioselective Friedel-Crafts Reactions in Water Using a DNA-Based Catalyst [J].

Boersma, Arnold J. ;

Feringa, Ben L. ;

Roelfes, Gerard .

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2009, 48 (18) :3346-3348

[5] DNA-Based catalytic enantioselective Michael reactions in water [J].

Coquiere, David ;

Feringa, Ben L. ;

Roelfes, Gerard .

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2007, 46 (48) :9308-9311

[6] A conserved quadruplex motif located in a transcription activation site of the human c-kit oncogene [J].

Fernando, Himesh ;

Reszka, Anthony P. ;

Huppert, Julian ;

Ladame, Sylvain ;

Rankin, Sarah ;

Venkitaraman, Ashok R. ;

Neidle, Stephen ;

Balasubramanian, Shankar .

BIOCHEMISTRY, 2006, 45 (25) :7854-7860

[7] Selectivity of small molecule ligands for parallel and anti-parallel DNA G-quadruplex structures [J].

Garner, Thomas P. ;

Williams, Huw E. L. ;

Gluszyk, Katarzyna I. ;

Roe, Stephen ;

Oldham, Neil J. ;

Stevens, Malcolm F. G. ;

Moses, John E. ;

Searle, Mark S. .

ORGANIC & BIOMOLECULAR CHEMISTRY, 2009, 7 (20) :4194-4200

[8] G-quadruplex compounds and cis-platin act synergistically to inhibit cancer cell growth in vitro and in vivo [J].

Gunaratnam, Mekala ;

Green, Colin ;

Moreira, Joao Bruno ;

Moorhouse, Adam D. ;

Kelland, Lloyd R. ;

Moses, John E. ;

Neidle, Stephen .

BIOCHEMICAL PHARMACOLOGY, 2009, 78 (02) :115-122

[9] Structure of the human telomere in K+ solution:: An intramolecular (3+1) G-quadruplex scaffold [J].

Luu, Kim Ngoc ;

Phan, Anh Tuan ;

Kuryavyi, Vitaly ;

Lacroix, Laurent ;

Patel, Dinshaw J. .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2006, 128 (30) :9963-9970

[10] A hitchhiker's guide to G-quadruplex ligands [J].

Monchaud, David ;

Teulade-Fichou, Marie-Paule .

ORGANIC & BIOMOLECULAR CHEMISTRY, 2008, 6 (04) :627-636

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