Association between heart rate-corrected QT interval and coronary risk factors in 2,894 healthy subjects (The DESIR study)

被引：24

作者：

Fauchier, L ^{[1
]}

Maison-Blanche, P

Forhan, A

D'Hour, A

Lépinay, P

Tichet, J

Vol, S

Coumel, P

Fauchier, JP

Balkau, B

机构：

[1] CHU Trousseau, Serv Cardiol B, F-37044 Tours, France

[2] CHU Trousseau, Lab Electrophysiol Cardiaque, F-37044 Tours, France

[3] Fac Med Paris Sud, Villejuif, France

[4] INSERM, U258, Villejuif, France

[5] Hop Lariboisiere, Serv Cardiol, F-75475 Paris, France

[6] Ctr Examens Sante, Le Mans, France

[7] Ctr Examens Sante, Orleans, France

[8] IRSA, La Riche, France

来源：

AMERICAN JOURNAL OF CARDIOLOGY | 2000年 / 86卷 / 05期

关键词：

D O I：

10.1016/S0002-9149(00)01015-8

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

In the prospective Data from an Epidemiological Study on the Insulin Resistance Syndrome, 2,894 healthy subjects aged 30 to 64 years had determinations of fasting glucose, insulin, serum lipid and fibrinogen concentrations, blood pressures, body mass index, and waist-hip ratio, as well as tobacco and alcohol consumptions and physical activity. A 12-lead electrocardiogram with automatic measurement of the QT interval was recorded and the formula used for heart rate correction was based on the best-fit regression between QT and heart rate. The QT duration was influenced by glucose homeostasis in both sexes, and increased in men with physical activity; there was a dose-effect relation for men who smoked.

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收藏

页码：557 / +

页数：4

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