Ultrathin, responsive polymer click capsules

被引：164

作者：

Such, Georgina K. ^{[1
]}

Tjipto, Elvira ^{[1
]}

Postma, Almar ^{[1
]}

Johnston, Angus P. R. ^{[1
]}

Caruso, Frank ^{[1
]}

机构：

[1] Univ Melbourne, Ctr Nanosci & Nanotechnol, Dept Chem & Biomol Engn, Melbourne, Vic 3010, Australia

来源：

NANO LETTERS | 2007年 / 7卷 / 06期

关键词：

D O I：

10.1021/nl070698f

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

We report a general click chemistry approach for the layer-by-layer assembly of ultrathin, polymer films on particles and the subsequent formation of polymer click capsules (CCs). Poly(acrylic acid) copolymers, synthesized with a minor component of either alkyne (PAA-Alk) or azide (PAA-Az) functionality, were alternately assembled on silica particles. The (PAA-Az/PAA-Alk)-coated particles were subsequently functionalized by exploiting the free alkyne click moieties present in the film upon exposure to an azide-modified rhodamine dye. Further, PAA CCs, obtained following removal of the silica particle template, were shown to exhibit pH-responsive behavior. This was demonstrated by reversible size changes of the CCs upon cycling between basic and acidic solutions. Polymer CCs are anticipated to find applications in various fields, including drug delivery and sensing.

引用

页码：1706 / 1710

页数：5

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