Direct-write dip-pen nanolithography of proteins on modified silicon oxide surfaces

被引：182

作者：

Lim, JH

Ginger, DS

Lee, KB

Heo, J

Nam, JM

Mirkin, CA

机构：

[1] Northwestern Univ, Dept Chem, Evanston, IL 60208 USA

[2] Northwestern Univ, Inst Nanotechnol, Evanston, IL 60208 USA

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2003年 / 42卷 / 20期

关键词：

biorecognition; direct-write patterns; nanostructures; proteins; surface chemistry;

D O I：

10.1002/anie.200351256

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Pen a nanoletter: Direct-write dip-pen nanolithography (DPN) has been used to generate protein nanostructures on modified silicon oxide surfaces. This technique offers control over feature size at the 50-550 nm scale. The bioactivity of the proteins remains intact and has been studied by fluorescence microscopy (see picture).

引用

收藏

页码：2309 / 2312

页数：4

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