Self-replication vs. reactive binary complexes -: manipulating recognition-mediated cycloadditions by simple structural modifications

被引:36
作者
Pearson, RJ [1 ]
Kassianidis, E [1 ]
Slawin, AMZ [1 ]
Philp, D [1 ]
机构
[1] Univ St Andrews, Ctr Biomol Sci, Sch Chem, St Andrews KY16 9ST, Fife, Scotland
基金
英国工程与自然科学研究理事会; 英国生物技术与生命科学研究理事会;
关键词
D O I
10.1039/b406862a
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
The rate of reaction and the selectivity of a Diels-Alder cycloaddition between a furan and a maleimide can be enhanced by the introduction of complementary recognition sites on the reactant species. Subtle manipulation of other structural elements allows the generation of the observed rate enhancements and selectivities through either self-replication or formation of a pre-reactive binary complex.
引用
收藏
页码:3434 / 3441
页数:8
相关论文
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