The versatile worm:: genetic and genomic resources for Caenorhabditis elegans research

被引：92

作者：

Antoshechkin, Igor

Sternberg, Paul W.

机构：

[1] CALTECH, Div Biol 156 29, Pasadena, CA 91125 USA

[2] CALTECH, Howard Hughes Med Inst, Pasadena, CA 91125 USA

来源：

NATURE REVIEWS GENETICS | 2007年 / 8卷 / 07期

关键词：

D O I：

10.1038/nrg2105

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Since its establishment as a model organism, Caenorhabditis elegans has been an invaluable tool for biological research. An immense spectrum of questions can be addressed using this small nematode, making it one of the most versatile and exciting model organisms. Although the many tools and resources developed by the C. elegans community greatly facilitate new discoveries, they can also overwhelm newcomers to the field. This Review aims to familiarize new worm researchers with the main resources, and help them to select the tools that are best suited for their needs. We also hope that it will be helpful in identifying new research opportunities and will promote the development of additional resources.

引用

页码：518 / 532

页数：15

共 66 条

[1] Automatic clustering of orthologs and inparalogs shared by multiple proteomes [J].

Alexeyenko, Andrey ;

Tamas, Ivica ;

Liu, Gang ;

Sonnhammer, Erik L. L. .

BIOINFORMATICS, 2006, 22 (14) :E9-E15

[2] Gene Ontology: tool for the unification of biology [J].

Ashburner, M ;

Ball, CA ;

Blake, JA ;

Botstein, D ;

Butler, H ;

Cherry, JM ;

Davis, AP ;

Dolinski, K ;

Dwight, SS ;

Eppig, JT ;

Harris, MA ;

Hill, DP ;

Issel-Tarver, L ;

Kasarskis, A ;

Lewis, S ;

Matese, JC ;

Richardson, JE ;

Ringwald, M ;

Rubin, GM ;

Sherlock, G .

NATURE GENETICS, 2000, 25 (01) :25-29

[3] The universal protein resource (UniProt) [J].

Bairoch, A ;

Apweiler, R ;

Wu, CH ;

Barker, WC ;

Boeckmann, B ;

Ferro, S ;

Gasteiger, E ;

Huang, HZ ;

Lopez, R ;

Magrane, M ;

Martin, MJ ;

Natale, DA ;

O'Donovan, C ;

Redaschi, N ;

Yeh, LSL .

NUCLEIC ACIDS RESEARCH, 2005, 33 :D154-D159

[4]

Ball CA, 2005, NUCLEIC ACIDS RES, V33, pD580

[5] EDGEdb:: a transcription factor-DNA Interaction database for the analysis of C-elegans differential gene expression [J].

Barrasa, M. Inmaculada ;

Vaglio, Philippe ;

Cavasino, Fabien ;

Jacotot, Laurent ;

Walhout, Albertha J. M. .

BMC GENOMICS, 2007, 8 (1)

[6]

Barrett T, 2005, NUCLEIC ACIDS RES, V33, pD562

[7]

Bateman A, 2002, NUCLEIC ACIDS RES, V30, P276, DOI [10.1093/nar/gkr1065, 10.1093/nar/gkp985, 10.1093/nar/gkh121]

[8] The Protein Data Bank [J].

Berman, HM ;

Westbrook, J ;

Feng, Z ;

Gilliland, G ;

Bhat, TN ;

Weissig, H ;

Shindyalov, IN ;

Bourne, PE .

NUCLEIC ACIDS RESEARCH, 2000, 28 (01) :235-242

[9] WormBase:: new content and better access [J].

Bieri, Tamberlyn ;

Blasiar, Darin ;

Ozersky, Philip ;

Antoshechkin, Igor ;

Bastiani, Carol ;

Canaran, Payan ;

Chan, Juancarlos ;

Chen, Nansheng ;

Chen, Wen J. ;

Davis, Paul ;

Fiedler, Tristan J. ;

Girard, Lisa ;

Han, Michael ;

Harris, Todd W. ;

Kishore, Ranjana ;

Lee, Raymond ;

McKay, Sheldon ;

Muller, Hans-Michael ;

Nakamura, Cecilia ;

Petcherski, Andrei ;

Rangarajan, Arun ;

Rogers, Anthony ;

Schindelman, Gary ;

Schwarz, Erich M. ;

Spooner, Will ;

Tuli, Mary Ann ;

Van Auken, Kimberly ;

Wang, Daniel ;

Wang, Xiaodong ;

Williams, Gary ;

Durbin, Richard ;

Stein, Lincoln D. ;

Sternberg, Paul W. ;

Spieth, John .

NUCLEIC ACIDS RESEARCH, 2007, 35 :D506-D510

[10] Genome sequence of the nematode C-elegans:: A platform for investigating biology [J].

不详 .

SCIENCE, 1998, 282 (5396) :2012-2018

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