An area specialized for spatial working memory in human frontal cortex

被引:728
作者
Courtney, SM [1 ]
Petit, L [1 ]
Maisog, JM [1 ]
Ungerleider, LG [1 ]
Haxby, JV [1 ]
机构
[1] NIMH, Lab Brain & Cognit, Bethesda, MD 20892 USA
关键词
D O I
10.1126/science.279.5355.1347
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Working memory is the proc!ss of maintaining an active representation of information so that it is available for use. In monkeys, a prefrontal cortical region important for spatial working memory lies in and around the principal sulcus, but in humans the location, and even the existence, of a region for spatial working memory is in dispute. By using functional magnetic resonance imaging in humans, an area in the superior frontal sulcus was identified that is specialized for spatial working memory. This area is located more superiorly and posteriorly in the human than in the monkey brain, which may explain why it was not recognized previously.
引用
收藏
页码:1347 / 1351
页数:5
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