Preparation and characterization of macroporous poly(2-hydroxyethyl methacrylate)-based biomaterials:: Water sorption property and in vitro blood compatibility

被引：30

作者：

Bajpai, A. K. ^{[1
]}

Kankane, Sanjana ^{[1
]}

机构：

[1] Govt Autonomous Sci Coll, Dept Chem, Bose Mem Res Lab, Jabalpur 482001, Madhya Pradesh, India

来源：

JOURNAL OF APPLIED POLYMER SCIENCE | 2007年 / 104卷 / 03期

关键词：

hydrogel; interpenetrating polymer network; swelling; blood compatibility;

D O I：

10.1002/app.25580

中图分类号：

O63 [高分子化学（高聚物）];

学科分类号：

070305 ; 080501 ; 081704 ;

摘要：

A semi-interpenetrating polymer network (IPN) comprising gelatin and poly(2-hydroxyethyl methacrylate-co-acrylamide) was prepared and characterized by FTIR, environmental scanning electron microscopy (ESEM) and differential scanning calorimetry (DSC) techniques. The water sorption potential of the prepared semi-IPNs was investigated for varying chemical architecture of the IPN, and experimental conditions such as pH, temperature and ionic strength of the swelling media. The semi-IPNs were also judged for in vitro blood compatibility by performing blood clot, percent hemolysis, protein adsorption and platelet adhesion tests. (c) 2007 Wiley Periodicals, Inc.

引用

页码：1559 / 1571

页数：13

共 58 条

[1]

Akaike T., 1997, Advances in Polymeric Biomaterials Science

[2] POLYVINYLPYRIDINE-ETHANOL SYSTEMS [J].

AKIN, H ;

HASIRCI, N .

JOURNAL OF APPLIED POLYMER SCIENCE, 1992, 46 (07) :1307-1310

[3] PREPARATION AND CHARACTERIZATION OF CROSS-LINKED GELATIN MICROSPHERES [J].

AKIN, H ;

HASIRCI, N .

JOURNAL OF APPLIED POLYMER SCIENCE, 1995, 58 (01) :95-100

[4] Biological responses to materials [J].

Anderson, JM .

ANNUAL REVIEW OF MATERIALS RESEARCH, 2001, 31 :81-110

[5]

[Anonymous], ENCYCLOPEDIA POLYMER

[6] Preparation and characterization of spongy cryogels of poly(vinyl alcohol)-casein system: water sorption and blood compatibility study [J].

Bajpai, A ;

Saini, R .

POLYMER INTERNATIONAL, 2005, 54 (05) :796-806

[7] Preparation and characterization of biocompatible spongy cryogels of poly(vinyl alcohol)-gelatin and study of water sorption behaviour [J].

Bajpai, AK ;

Saini, R .

POLYMER INTERNATIONAL, 2005, 54 (09) :1233-1242

[8] Release and diffusion of sulfamethoxazole through acrylamide-based hydrogel [J].

Bajpai, AK ;

Rajpoot, M .

JOURNAL OF APPLIED POLYMER SCIENCE, 2001, 81 (05) :1238-1247

[9] Adsorption dynamics of bovine serum albumin (BSA) onto binary interpenetrating polymer networks (IPNs) of poly(2-hydroxyethyl methacrylate) (PHEMA) [J].

Bajpai, AK ;

Shrivastava, M .

JOURNAL OF MACROMOLECULAR SCIENCE-PURE AND APPLIED CHEMISTRY, 2001, 38 (11) :1123-1139

[10]

Baker RW, 1974, CONTROLLED RELEASE M

← 1 2 3 4 5 6 →