Novel and efficient catalysts for the one-pot synthesis of 3,4-dihydropyrano[c]chromene derivatives in aqueous media

被引:295
作者
Abdolmohammadi, Shahrzad
Balalaie, Saeed
机构
[1] KN Toosi Univ Technol, Peptide Chem Res Grp, Tehran, Iran
[2] Univ Tehran, Coll Sci, Sch Chem, Tehran, Iran
关键词
D O I
10.1016/j.tetlet.2007.02.135
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Diammonium hydrogen phosphate, (NH(4))(2)HPO(4)(DAHP), efficiently catalyzes the one-pot, three-component reaction of an aromatic aldehyde, malononitrile and 4-hydroxycoumarin in aqueous media under mild conditions at room temperature, to afford the corresponding dihydropyrano[c]chromenes in high yields. (S)-Proline has also been used as another neutral catalyst for this reaction at reflux. (c) 2007 Elsevier Ltd. All rights reserved.
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页码:3299 / 3303
页数:5
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