Clinical implications of obesity with specific focus on cardiovascular disease - A statement for professionals from the American Heart Association Council on Nutrition, Physical Activity, and Metabolism - Endorsed by the American College of Cardiology Foundation

被引:649
作者
Klein, S [1 ]
Burke, LE [1 ]
Bray, GA [1 ]
Blair, S [1 ]
Allison, DB [1 ]
Pi-Sunyer, X [1 ]
Hong, YL [1 ]
Eckel, RH [1 ]
机构
[1] Amer Heart Assoc, Dallas, TX 75231 USA
关键词
AHA Scientific Statements; obesity; cardiovascular diseases; exercise; diet;
D O I
10.1161/01.CIR.0000145546.97738.1E
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Obesity adversely affects cardiac function, increases the risk factors for coronary heart disease, and is an independent risk factor for cardiovascular disease. The risk of developing coronary heart disease is directly related to the concomitant burden of obesity-related risk factors. Modest weight loss can improve diastolic function and affect the entire cluster of coronary heart disease risk factors simultaneously. This statement from the American Heart Association Council on Nutrition, Physical Activity, and Metabolism reviews the relationship between obesity and the cardiovascular system, evaluates the effect of weight loss on coronary heart disease risk factors and coronary heart disease, and provides practical weight management treatment guidelines for cardiovascular healthcare professionals. The data demonstrate that weight loss and physical activity can prevent and treat obesity-related coronary heart disease risk factors and should be considered a primary therapy for obese patients with cardiovascular disease.
引用
收藏
页码:2952 / 2967
页数:16
相关论文
共 211 条
[71]   Weight reduction regresses left ventricular mass regardless of blood pressure level in obese subjects [J].
Himeno, E ;
Nishino, K ;
Nakashima, Y ;
Kuroiwa, A ;
Ikeda, M .
AMERICAN HEART JOURNAL, 1996, 131 (02) :313-319
[72]   Reduction of left ventricular hypertrophy after exercise and weight loss in overweight patients with mild hypertension [J].
Hinderliter, A ;
Sherwood, A ;
Gullette, ECD ;
Babyak, M ;
Waugh, R ;
Georgiades, A ;
Blumenthal, JA .
ARCHIVES OF INTERNAL MEDICINE, 2002, 162 (12) :1333-1339
[73]   HEART-RATE-VARIABILITY AS A MEASURE OF AUTONOMIC FUNCTION DURING WEIGHT CHANGE IN HUMANS [J].
HIRSCH, J ;
LEIBEL, RL ;
MACKINTOSH, R ;
AGUIRRE, A .
AMERICAN JOURNAL OF PHYSIOLOGY, 1991, 261 (06) :R1418-R1423
[74]   Role of orlistat in the treatment of obese patients with type 2 diabetes - A 1-year randomized double-blind study [J].
Hollander, PA ;
Elbein, SC ;
Hirsch, IB ;
Kelley, D ;
McGill, J ;
Taylor, T ;
Weiss, SR ;
Crockett, SE ;
Kaplan, RA ;
Comstock, J ;
Lucas, CP ;
Lodewick, PA ;
Canovatchel, W ;
Chung, J ;
Hauptman, J .
DIABETES CARE, 1998, 21 (08) :1288-1294
[75]   GASTRIC BYPASS AND VERTICAL BANDED GASTROPLASTY - A PROSPECTIVE RANDOMIZED COMPARISON AND 5-YEAR FOLLOW-UP [J].
HOWARD, L ;
MALONE, M ;
MICHALEK, A ;
CARTER, J ;
ALGER, S ;
VANWOERT, J .
OBESITY SURGERY, 1995, 5 (01) :55-60
[76]   Body weight, weight change, and risk for hypertension in women [J].
Huang, ZP ;
Willett, WC ;
Manson, JE ;
Rosner, B ;
Stampfer, MJ ;
Speizer, FE ;
Colditz, GA .
ANNALS OF INTERNAL MEDICINE, 1998, 128 (02) :81-+
[77]   Cardiovascular morbidity and mortality associated with the metabolic syndrome [J].
Isomaa, B ;
Almgren, P ;
Tuomi, T ;
Forsén, B ;
Lahti, K ;
Nissén, M ;
Taskinen, MR ;
Groop, L .
DIABETES CARE, 2001, 24 (04) :683-689
[78]   Effects of intermittent exercise and use of home exercise equipment on adherence, weight loss, and fitness in overweight women - A randomized trial [J].
Jakicic, JM ;
Winters, C ;
Lang, W ;
Wing, RR .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1999, 282 (16) :1554-1560
[79]  
JAKICIC JM, 1995, INT J OBESITY, V19, P893
[80]   Appropriate strategies for intervention weight loss and prevention of weight regain for adults [J].
Jakicic, JM ;
Clark, K ;
Coleman, E ;
Donnelly, JE ;
Foreyt, J ;
Melanson, E ;
Volek, J ;
Volpe, SL .
MEDICINE AND SCIENCE IN SPORTS AND EXERCISE, 2001, 33 (12) :2145-2156