Allosterically controllable ribozymes with biosensor functions

被引：32

作者：

Kuwabara, T

Warashina, M

Taira, K ^{[1
]}

机构：

[1] Univ Tokyo, Grad Sch Engn, Dept Chem & Biotechnol, Tokyo 1138656, Japan

[2] AIST, Agcy Ind Sci & Technol, Natl Inst Adv Interdisciplinary Res, Tsukuba, Ibaraki 3058562, Japan

来源：

CURRENT OPINION IN CHEMICAL BIOLOGY | 2000年 / 4卷 / 06期

关键词：

D O I：

10.1016/S1367-5931(00)00150-2

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The concept of allosteric regulation has already been exploited in the creation of artificial ribozymes and the activities of certain ribozymes can be controlled allosterically by specific effecters. Ribozymes with such properties are in the spotlight as biosensors. Such artificial allosterically regulated ribozymes have potential utility as nucleic-acid-based biosensors.

引用

页码：669 / 677

页数：9

共 53 条

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