Solvent free catalytic C-H functionalisation

被引:76
作者
Bedford, Robin B. [1 ]
Mitchell, Charlotte J. [2 ]
Webster, Ruth L. [1 ]
机构
[1] Univ Bristol, Sch Chem, Bristol BS8 1TS, Avon, England
[2] GlaxoSmithKline, Stevenage SG1 2NY, Herts, England
基金
英国工程与自然科学研究理事会;
关键词
ACTIVATION; ARYLATION;
D O I
10.1039/c003074k
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Solvent-free reaction conditions facilitate a range of aromatic C-H functionalisations that traditionally require acidic or disfavoured solvents. These reactions include selective ortho and meta-arylation of aryl carbamates and anilides and selective halogenation reactions.
引用
收藏
页码:3095 / 3097
页数:3
相关论文
共 19 条
[1]   Aryl-aryl bond formation by transition-metal-catalyzed direct arylation [J].
Alberico, Dino ;
Scott, Mark E. ;
Lautens, Mark .
CHEMICAL REVIEWS, 2007, 107 (01) :174-238
[2]  
[Anonymous], 2008, TETRAHEDRON, V64, P5963
[3]   Palladium-catalysed ortho-arylation of carbamate-protected phenols [J].
Bedford, Robin B. ;
Webster, Ruth L. ;
Mitchell, Charlotte J. .
ORGANIC & BIOMOLECULAR CHEMISTRY, 2009, 7 (23) :4853-4857
[4]   Palladium(II)-Catalyzed C-H Activation/C-C Cross-Coupling Reactions: Versatility and Practicality [J].
Chen, Xiao ;
Engle, Keary M. ;
Wang, Dong-Hui ;
Yu, Jin-Quan .
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2009, 48 (28) :5094-5115
[5]   Introduction to Selective Functionalization of C-H Bonds [J].
Crabtree, Robert H. .
CHEMICAL REVIEWS, 2010, 110 (02) :575-575
[6]   Anilide ortho-arylation by using C-H activation methodology [J].
Daugulis, O ;
Zaitsev, VG .
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2005, 44 (26) :4046-4048
[7]  
Dyker G, 2005, HANDBOOK OF C-H TRANSFORMATIONS: APPLICATIONS IN ORGANIC SYNTHESIS, VOL 1, pV
[8]   C-H bond functionalization in complex organic synthesis [J].
Godula, K ;
Sames, D .
SCIENCE, 2006, 312 (5770) :67-72
[9]   A simple catalytic method for the regioselective halogenation of arenes [J].
Kalyani, Dipannita ;
Dick, Allison R. ;
Anani, Waseem Q. ;
Sanford, Melanie S. .
ORGANIC LETTERS, 2006, 8 (12) :2523-2526
[10]   Room Temperature C-H Activation and Cross-Coupling of Aryl Ureas in Water [J].
Nishikata, Takashi ;
Abela, Alexander R. ;
Lipshutz, Bruce H. .
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2010, 49 (04) :781-784