Synthesis and anti-HIV activity of substituted 1 2,4-triazolo-thiophene derivatives

被引:11
作者
Al-Soud, Yaseen A. [1 ]
机构
[1] Univ Al Al Bayt, Coll Sci, Dept Chem, Al Mafraq, Jordan
关键词
D O I
10.1002/hc.20319
中图分类号
O6 [化学];
学科分类号
0703 [化学];
摘要
A new series of substituted 1,2,4-triazoles bearing thiophene molecules 8 and 10 has been synthesized from cycloaddition of thiophene 3-and 2-carbonitriles 5 and 9, respectively, with the reactive cumulene intermediates 4. The newly synthesized products have been evaluated for their anti-HIV activity. (c) 2007 Wiley Periodicals, Inc.
引用
收藏
页码:443 / 448
页数:6
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