Pyridine adducts of chiral arene ruthenium compounds. Diastereoselective synthesis and characterization

被引：19

作者：

Faller, JW ^{[1
]}

Grimmond, BJ ^{[1
]}

Curtis, M ^{[1
]}

机构：

[1] Yale Univ, Dept Chem, New Haven, CT 06520 USA

来源：

ORGANOMETALLICS | 2000年 / 19卷 / 24期

关键词：

D O I：

10.1021/om000319s

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

The compounds [CyRu(eta (2)-Ph2PCH(Me)Ph2PO)L] [SbF6](2), where Cy = p-CH3C6H4CH(CH3)(2); L = pyridine, 2; 3,5-lutidine, 3; isoquinoline, 4, were synthesized by chloride abstraction from [CyRu(eta (2)-Ph2PCH(Me)Ph2PO)Cl] [SbF6], 1, followed by treatment of the intermediate Lewis acid [CyRu(eta (2)-Ph2PCH(Me)Ph2PO)][SbF6](2) with the appropriate ligand. Characterization by elemental analysis, H-1, P-31(H-1), VT NMR spectroscopy, and IR spectroscopy indicated that 2-4 were obtained as a mixture of exo and endo diastereomers (de = 14-60%). The endo diastereomer of compound 2 was also characterized by X-ray crystallography which revealed the (R-Ru*,R-C*) relative configuration of the two stereogenic centers within the molecule. In contrast to analogues with other neutral donors, P-31{H-1} NMR spectroscopy experiments demonstrated that 2-4 were stable to diastereomer interconversion in solution. This suggests that epimerization of the ruthenium center in an intermediate exo-[CyRu(eta (2)-Ph2PCH(Me)Ph2PO)] [SbF6](2) occurred by a path unavailable to 2-4 by inversion of the Ru(eta (2)-Ph2PCH(Me)Ph2PO) ring.

引用

页码：5174 / 5181

页数：8

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[1] SIR92 - a program for automatic solution of crystal structures by direct methods [J].