An imine addition/ring-closing metathesis approach to the spirocyclic core of halichlorine and pinnaic acid

被引：163

作者：

Wright, DL ^{[1
]}

Schulte, JP ^{[1
]}

Page, MA ^{[1
]}

机构：

[1] Univ Florida, Dept Chem, Gainesville, FL 32611 USA

来源：

ORGANIC LETTERS | 2000年 / 2卷 / 13期

关键词：

D O I：

10.1021/ol005903b

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An approach to the spirocyclic core of halichlorine and pinnaic acid has been designed around an imine allylation/ring-closing metathesis sequence. This sequence has been used to generate several azabicylo[n.5] model systems. A newly reported metathesis catalyst was show to be highly effective for cyclization of these systems.

引用

页码：1847 / 1850

页数：4

共 24 条

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