Cascade and sequential palladium catalysed cyclisation-azide capture-1,3-dipolar cycloaddition route to complex triazoles.

被引：59

作者：

Gardiner, M

Grigg, R ^{[1
]}

Sridharan, V

Vicker, N

机构：

[1] Univ Leeds, Sch Chem, Leeds LS2 9JT, W Yorkshire, England

[2] Rhone Poulenc Rorer, Dagenham Res Ctr, Dagenham RM10 7XS, England

来源：

TETRAHEDRON LETTERS | 1998年 / 39卷 / 5-6期

基金：

英国工程与自然科学研究理事会;

关键词：

D O I：

10.1016/S0040-4039(97)10541-X

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Palladium catalysed processes involving sequential cyclisation of aryl iodides onto proximate allenes with capture by NaN3 (and NaO2SPh) followed by a 1,3-dipolar cycloaddition reaction utilizing DMAD, methyl propiolate and norbomadiene are described. When utilising the latter, the sequence can be carried out as a one-pot protocol which terminates with a retro Diels-Alder reaction. (C) 1997 Elsevier Science Ltd. All rights reserved.

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页码：435 / 438

页数：4

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