Genetic linkage and association analyses for trait mapping in Plasmodium falciparum

被引：64

作者：

Su, Xinzhuan ^{[1
]}

Hayton, Karen ^{[1
]}

Wellems, Thomas E. ^{[1
]}

机构：

[1] NIAID, Lab Malaria & Vector Res, NIH, Bethesda, MD 20892 USA

来源：

NATURE REVIEWS GENETICS | 2007年 / 8卷 / 07期

关键词：

D O I：

10.1038/nrg2126

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Genetic studies of Plasmodium falciparum laboratory crosses and field isolates have produced valuable insights into determinants of drug responses, antigenic variation, disease virulence, cellular development and population structures of these virulent human malaria parasites. Full-genome sequences and high-resolution haplotype maps of SNPs and microsatellites are now available for all 14 parasite chromosomes. Rapidly increasing genetic and genomic information on Plasmodium parasites, mosquitoes and humans will combine as a rich resource for new advances in our understanding of malaria, its transmission and its manifestations of disease.

引用

页码：497 / 506

页数：10

共 118 条

[101] A genome-wide map of diversity in Plasmodium falciparum [J].

Volkman, Sarah K. ;

Sabeti, Pardis C. ;

DeCaprio, David ;

Neafsey, Daniel E. ;

Schaffner, Stephen F. ;

Milner, Danny A., Jr. ;

Daily, Johanna P. ;

Sarr, Ousmane ;

Ndiaye, Daouda ;

Ndir, Omar ;

Mboup, Soulyemane ;

Duraisingh, Manoj T. ;

Lukens, Amanda ;

Derr, Alan ;

Stange-Thomann, Nicole ;

Waggoner, Skye ;

Onofrio, Robert ;

Ziaugra, Liuda ;

Mauceli, Evan ;

Gnerre, Sante ;

Jaffe, David B. ;

Zainoun, Joanne ;

Wiegand, Roger C. ;

Birren, Bruce W. ;

Hartl, Daniel L. ;

Galagan, James E. ;

Lander, Eric S. ;

Wirth, Dyann F. .

NATURE GENETICS, 2007, 39 (01) :113-119

[102] Recent origin of Plasmodium falciparum from a single progenitor [J].

Volkman, SK ;

Barry, AE ;

Lyons, EJ ;

Nielsen, KM ;

Thomas, SM ;

Choi, M ;

Thakore, SS ;

Day, KP ;

Wirth, DF ;

Hartl, DL .

SCIENCE, 2001, 293 (5529) :482-484

[103] GENETIC-ANALYSIS OF THE HUMAN MALARIA PARASITE PLASMODIUM-FALCIPARUM [J].

WALLIKER, D ;

QUAKYI, IA ;

WELLEMS, TE ;

MCCUTCHAN, TF ;

SZARFMAN, A ;

LONDON, WT ;

CORCORAN, LM ;

BURKOT, TR ;

CARTER, R .

SCIENCE, 1987, 236 (4809) :1661-1666

[104] GENETIC RECOMBINATION IN MALARIA PARASITES [J].

WALLIKER, D ;

CARTER, R ;

MORGAN, S .

NATURE, 1971, 232 (5312) :561-&

[105]

Walliker David, 1998, P235

[106] Genetic and metabolic analysis of folate salvage in the human malaria parasite Plasmodium falciparum [J].

Wang, P ;

Nirmalan, N ;

Wang, Q ;

Sims, PFG ;

Hyde, JE .

MOLECULAR AND BIOCHEMICAL PARASITOLOGY, 2004, 135 (01) :77-87

[107] Sulfadoxine resistance in the human malaria parasite Plasmodium falciparum is determined by mutations in dihydropteroate synthetase and an additional factor associated with folate utilization [J].

Wang, P ;

Read, M ;

Sims, PFG ;

Hyde, JE .

MOLECULAR MICROBIOLOGY, 1997, 23 (05) :979-986

[108] GENETIC-MAPPING OF THE CHLOROQUINE-RESISTANCE LOCUS ON PLASMODIUM-FALCIPARUM CHROMOSOME-7 [J].

WELLEMS, TE ;

WALKERJONAH, A ;

PANTON, LJ .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1991, 88 (08) :3382-3386

[109] Chloroquine-resistant malaria [J].

Wellems, TE ;

Plowe, CV .

JOURNAL OF INFECTIOUS DISEASES, 2001, 184 (06) :770-776

[110] CHLOROQUINE RESISTANCE NOT LINKED TO MDR-LIKE GENES IN A PLASMODIUM-FALCIPARUM CROSS [J].

WELLEMS, TE ;

PANTON, LJ ;

GLUZMAN, IY ;

DOROSARIO, VE ;

GWADZ, RW ;

WALKERJONAH, A ;

KROGSTAD, DJ .

NATURE, 1990, 345 (6272) :253-255

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