Helicobacter pylori:: recombination, population structure and human migrations

被引:43
作者
Suerbaum, S
Achtman, M
机构
[1] Hannover Med Sch, Inst Med Mikrobiol & Krankenhaushyg, D-30625 Hannover, Germany
[2] Max Planck Inst Infektiosbiol, Abt Molekularbiol, D-10117 Berlin, Germany
关键词
Helicobacter pylori; population genetics; microevolution;
D O I
10.1016/j.ijmm.2004.06.014
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Helicobacter pylori shows extensive genetic diversity and variability due to frequent intraspecific recombination during mixed infection. In the last years, modern genetic and genomic technology as well as cutting-edge population genetic analysis have been used to investigate the population structure and genetic variability of this pathogen. This review article summarizes recent developments in this rapidly moving field. (C) 2004 Elsevier GmbH. All rights reserved.
引用
收藏
页码:133 / 139
页数:7
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